ICA-105665 is a research compound that acts as a potent, orally active opener of neuronal Kv7.2/7.3 and Kv7.3/7.5 potassium channels. It has demonstrated antiseizure activity in multiple animal models, has been evaluated clinically, and affects mitochondrial function and bile salt export at higher concentrations. Intended for research use only.
- Potent neuronal Kv7 channel opener, active orally.
- Demonstrated antiseizure activity in multiple in vivo models.
- Suitable for electrophysiology and preclinical pharmacology studies.
- High purity (>99.8%) solid for analytical and biological work.
- Soluble in DMSO at about 250 mg/mL with ultrasonic assistance.
- Powder form with storage at -20°C for long term or 4°C for short term.
- Datasheet, COA, and SDS available for quality and handling information.
- Not for human or clinical use; research use only.